The present invention provides for method of seeking synchronization at a data interface between a transmitting element and a receiving element, and to related transmitting and receiving elements of the interface, in which the clock frequency of both elements is the same but which exhibit a phase difference, also known as mesochronous clock domains, the method including the steps of, prior to data transfer at the interface, delivering a strobe signal generated at the transmitting element to the receiving element, generating a strobe signal at the receiving element and synchronizing the same to the strobe signal received from the transmitting element, and maintaining the synchronized strobe signal generated at the receiving element for the sampling of data appearing at the interface from the transmitting element.