Invention Grant
US08258331B2 Method for preparation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine, and use therof
有权
制备N-甲基-3-(2-三丁基甲锡烷基苯氧基)-3-苯基丙胺的方法,并使用该方法
- Patent Title: Method for preparation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine, and use therof
- Patent Title (中): 制备N-甲基-3-(2-三丁基甲锡烷基苯氧基)-3-苯基丙胺的方法,并使用该方法
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Application No.: US13087862Application Date: 2011-04-15
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Publication No.: US08258331B2Publication Date: 2012-09-04
- Inventor: Show-Wen Liu , Cheng-Hsien Lin , Tsyh-Lang Lin , Cheng-Fang Hsu , Yu Chang
- Applicant: Show-Wen Liu , Cheng-Hsien Lin , Tsyh-Lang Lin , Cheng-Fang Hsu , Yu Chang
- Applicant Address: TW Taoyuan County
- Assignee: Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
- Current Assignee: Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
- Current Assignee Address: TW Taoyuan County
- Agency: WPAT, PC
- Agent Justin King
- Priority: TW99120267A 20100622
- Main IPC: C07F7/22
- IPC: C07F7/22 ; C07C217/00

Abstract:
A method for preparation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine is provided, which includes formation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine, useful as a precursor of a norepinephrine transporter (NET) contrast label [123Iodine](R)—N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine ([123I]MIPP) with a leaving group Bu3Sn.
Public/Granted literature
- US20110313183A1 METHOD FOR PREPARATION OF N-METHYL-3-(2-TRIBUTYLSTANNYLPHENOXY)-3-PHENYLPROPANAMINE, AND USE THEROF Public/Granted day:2011-12-22
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