Invention Grant
US08258263B2 Interferon-antibody fusion proteins demonstrating potent apoptotic and anti-tumor activities
有权
干扰素抗体融合蛋白表现出有力的凋亡和抗肿瘤活性
- Patent Title: Interferon-antibody fusion proteins demonstrating potent apoptotic and anti-tumor activities
- Patent Title (中): 干扰素抗体融合蛋白表现出有力的凋亡和抗肿瘤活性
-
Application No.: US12650329Application Date: 2009-12-30
-
Publication No.: US08258263B2Publication Date: 2012-09-04
- Inventor: Sherie L. Morrison , Tzu-Hsuan Huang , Caiyun Xuan
- Applicant: Sherie L. Morrison , Tzu-Hsuan Huang , Caiyun Xuan
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Weaver Austin Villeneuve & Sampson LLP
- Agent Tom Hunter
- Main IPC: A61K38/21
- IPC: A61K38/21 ; A61K39/00 ; A61K39/395 ; C12P21/00 ; C07K14/555 ; C07K16/30 ; C07K16/00 ; C07K16/46
Abstract:
Novel chimeric moieties that show significant efficacy against cancers are provided. In certain embodiments the chimeric moieties comprise a targeting moiety attached to an interferon. In certain embodiments, the chimeric moieties comprise fusion proteins where an antibody that specifically binds to a cancer marker is fused to interferon alpha (IFN-α) or interferon beta (IFN-β).
Public/Granted literature
- US20100172868A1 TARGETED INTERFERONS DEMONSTRATE POTENT APOPTOTIC AND ANTI-TUMOR ACTIVITIES Public/Granted day:2010-07-08
Information query
IPC分类:
