Invention Grant
- Patent Title: Pyridazinone glucokinase activators
- Patent Title (中): 哒嗪酮葡萄糖激酶激活剂
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Application No.: US12400319Application Date: 2009-03-09
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Publication No.: US08258134B2Publication Date: 2012-09-04
- Inventor: Steven Joseph Berthel , Nancy-Ellen Haynes , Robert Francis Kester , Lee Apostle McDermott , Yimin Qian , Ramakanth Sarabu , Nathan Robert Scott , Jefferson Wright Tilley
- Applicant: Steven Joseph Berthel , Nancy-Ellen Haynes , Robert Francis Kester , Lee Apostle McDermott , Yimin Qian , Ramakanth Sarabu , Nathan Robert Scott , Jefferson Wright Tilley
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- Main IPC: C07D401/06
- IPC: C07D401/06 ; C07D401/14 ; C07D237/32 ; C07D237/10 ; A61K31/501 ; A61K31/502 ; A61P5/50

Abstract:
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
Public/Granted literature
- US20090264434A1 PYRIDAZINONE GLUCOKINASE ACTIVATORS Public/Granted day:2009-10-22
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