Invention Grant
US08257688B2 Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues
失效
用于局部治疗指甲和周围组织的真菌感染的抗真菌和角质分解剂的受控递送系统
- Patent Title: Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues
- Patent Title (中): 用于局部治疗指甲和周围组织的真菌感染的抗真菌和角质分解剂的受控递送系统
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Application No.: US12652331Application Date: 2010-01-05
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Publication No.: US08257688B2Publication Date: 2012-09-04
- Inventor: Michael Friedman , Daniella Licht , Avraham Yacobi
- Applicant: Michael Friedman , Daniella Licht , Avraham Yacobi
- Applicant Address: IL Haifa Bay
- Assignee: Taro Pharmaceuticals Industries
- Current Assignee: Taro Pharmaceuticals Industries
- Current Assignee Address: IL Haifa Bay
- Agency: Venable LLP
- Agent Keith G. Haddaway; Michael E. Nelson
- Main IPC: A61K8/18
- IPC: A61K8/18
Abstract:
A topical sustained release delivery system for delivery of antifungal agents to the finger or toenails achieving high penetration through the nails by combining the antifungal agent with a keratolytic agent and a humectant. The pharmaceutical sustained release topical preparation is provided in a varnish or spray form for treating the nail and surrounding tissues, where the active ingredient is an antifungal agent, a keratolytic agent or combination thereof. The composition may further include an antibacterial, an antiviral, an antipsoriatic agents, or combinations thereof.
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