A framework for to enable collaborative research includes enabling scientific researchers to dynamically interact with others, collaboratively author, annotate, review, comment on others' data, and discuss their research. The framework allows for providing a dynamic collaboration environment by harnessing collective contributions from a group of researchers and facilitating broader participation of people into research projects. The framework is a Web-based collaborative platform to dynamically integrate information for scientific research. Besides data integration, the system provides essential collaboration capabilities to boost user participation and collaboration. The system will not only enable users as active information contributors to bring significant new values to the data, but also provide an environment for scientific researchers to do collaborative research in a large research community.