In embodiments of print plug-in isolation, a print system input can be received at a print system, and the print system input can be redirected from the print system to an isolation module that isolates one or more print plug-ins from the print system. The print system input can be processed at the isolation module with the one or more print plug-ins to generate print plug-in output, and the print plug-in output can then be communicated back to the print system from the isolation module.