Invention Grant
- Patent Title: Compound and use thereof in the treatment of amyloidosis
- Patent Title (中): 化合物及其在治疗淀粉样变性中的应用
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Application No.: US12728361Application Date: 2010-03-22
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Publication No.: US08236984B2Publication Date: 2012-08-07
- Inventor: Mark Brian Pepys , Steven Victor Ley , Angus John Morrison , Vittorio Bellotti , Simon Kolstoe , Martin Smith
- Applicant: Mark Brian Pepys , Steven Victor Ley , Angus John Morrison , Vittorio Bellotti , Simon Kolstoe , Martin Smith
- Applicant Address: GB London
- Assignee: Pentraxin Therapeutics Ltd.
- Current Assignee: Pentraxin Therapeutics Ltd.
- Current Assignee Address: GB London
- Agency: Vedder Price P.C.
- Agent Thomas J. Kowalski; Raymond Chung
- Priority: GB0718718.0 20070925
- Main IPC: C07C63/33
- IPC: C07C63/33 ; A01N37/30

Abstract:
The present invention relates to compounds of formula (I) for stabilizing the tetrameric form of transthyretin, compounds for use in the treatment or prevention of amyloidosis, and agents and medicaments comprising such compounds. wherein X, Y, R1, R2, R3, R4, m, n, p, q, and the linker are as defined herein.
Public/Granted literature
- US20100249233A1 COMPOUND AND USE THEREOF IN THE TREATMENT OF AMYLOIDOSIS Public/Granted day:2010-09-30
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