Invention Grant
- Patent Title: Tricyclic spiro derivatives as CRTH2 modulators
- Patent Title (中): 三环螺衍生物作为CRTH2调节剂
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Application No.: US11919471Application Date: 2006-05-23
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Publication No.: US08236963B2Publication Date: 2012-08-07
- Inventor: Matthias Schwarz , Eric Sebille , Christophe Cleva , Cedric Merlot , Dennis Church , Patrick Page , Jacqueline A. Macritchie , John Frederick Atherall , Stefano Crosignani , Doris Pupowicz
- Applicant: Matthias Schwarz , Eric Sebille , Christophe Cleva , Cedric Merlot , Dennis Church , Patrick Page , Jacqueline A. Macritchie , John Frederick Atherall , Stefano Crosignani , Doris Pupowicz
- Applicant Address: CH Vaud
- Assignee: Merck Serono SA
- Current Assignee: Merck Serono SA
- Current Assignee Address: CH Vaud
- Agency: EMD Serono Research Institute
- Priority: EP05104428 20050524
- International Application: PCT/EP2006/062545 WO 20060523
- International Announcement: WO2006/125784 WO 20061130
- Main IPC: C07D277/20
- IPC: C07D277/20 ; C07D271/06 ; C07D417/14 ; C07D487/10 ; C07D261/06 ; A61K31/44 ; A61K31/431 ; A61K31/4184 ; A61K31/4196 ; A61K31/41
Abstract:
The present invention is related to the use of spiro derivatives of Formula (I) for the treatment and/or prevention of allergic diseases, inflammatory dermatoses and other diseases with an inflammatory component. Specifically, the present invention is related to the use of spiro derivatives for the modulation of CRTH2 activity.
Public/Granted literature
- US20090318486A1 Tricyclic spiro derivatives as CRTH2 modulators Public/Granted day:2009-12-24
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