Invention Grant
- Patent Title: SiRNA targeting glucagon receptor (GCGR)
- Patent Title (中): 靶向胰高血糖素受体（GCGR）的SiRNA
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Application No.: US12798906Application Date: 2010-04-13
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Publication No.: US08236942B2Publication Date: 2012-08-07
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for GCGR.
Public/Granted literature
- US20100240554A1 siRNA Targeting Glucagon Receptor (GCGR) Public/Granted day:2010-09-23
Information query
