Invention Grant
- Patent Title: Tetracycline repressor regulated oncolytic viruses
- Patent Title (中): 四环素阻遏物调节溶瘤病毒
-
Application No.: US12553051Application Date: 2009-09-02
-
Publication No.: US08236941B2Publication Date: 2012-08-07
- Inventor: Feng Yao
- Applicant: Feng Yao
- Applicant Address: US MA Boston
- Assignee: The Brigham and Women's Hospital, Inc.
- Current Assignee: The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US MA Boston
- Agency: Law Office of: Michael A. Sanzo, LLC
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/79
Abstract:
The present invention is directed oncolytic Herpes simplex-1 viruses whose replication is controlled using a tetracycline operator/repressor system. The invention also includes DNA sequences used in making the viruses and methods in which these viruses are used in the treatment of cancer patients with solid tumors.
Public/Granted literature
- US20100015687A1 Tetracycline Repressor Regulated Oncolytic Viruses Public/Granted day:2010-01-21
Information query
