Invention Grant
- Patent Title: Production of recombinant selenoprotein mutants with enhanced catalytic activity
- Patent Title (中): 生产具有增强催化活性的重组硒蛋白突变体
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Application No.: US11922707Application Date: 2006-06-21
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Publication No.: US08236936B2Publication Date: 2012-08-07
- Inventor: Richard Sayre , Hangsik Moon
- Applicant: Richard Sayre , Hangsik Moon
- Applicant Address: US OH Columbus
- Assignee: Ohio State University
- Current Assignee: Ohio State University
- Current Assignee Address: US OH Columbus
- Agency: Global Patent Group, LLC
- International Application: PCT/US2006/024093 WO 20060621
- International Announcement: WO2007/002163 WO 20070104
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07H21/04
Abstract:
The present invention generally relates to the production of industrially relevant quantities of selenoprotein enzymes in eukaryotic cell cultures. More specifically, the present invention generally relates to the production of such enzymes wherein one or more catalytic cysteine or serine residues are mutagenically replaced by selenocysteine.
Public/Granted literature
- US20100159511A1 PRODUCTION OF RECOMBINANT SELENOPROTEIN MUTANTS WITH ENHANCED CATALYTIC ACTIVITY Public/Granted day:2010-06-24
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