Invention Grant
- Patent Title: Crystal forms of saxagliptin and processes for preparing same
- Patent Title (中): 沙格列汀的晶体形式及其制备方法
-
Application No.: US13081341Application Date: 2011-04-06
-
Publication No.: US08236847B2Publication Date: 2012-08-07
- Inventor: Jack Z. Gougoutas , Mary F. Malley , John D. DiMarco , Xiaotian S. Yin , Chenkou Wei , Jurong Yu , Truc Chi Vu , Gregory Scott Jones , Scott A. Savage
- Applicant: Jack Z. Gougoutas , Mary F. Malley , John D. DiMarco , Xiaotian S. Yin , Chenkou Wei , Jurong Yu , Truc Chi Vu , Gregory Scott Jones , Scott A. Savage
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K31/403
- IPC: A61K31/403 ; C07D209/02

Abstract:
Physical crystal structures of a compound of the formula I: are provided including the free base monohydrate thereof (form H-1) and the hydrochloric acid salt thereof, including hydrochloric acid salt containing 0.75 equivalent of H2O (form H0.75-3) and hydrochloric acid salt containing 2 equivalents of H2O (form H2-1), and hydrochloric acid salt Pattern P-5, preferably in substantially pure form, and other forms as described herein, pharmaceutical compositions containing structures of compound I or IA, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.
Public/Granted literature
- US20110257085A1 Crystal Forms of Saxagliptin and Processes for Preparing Same Public/Granted day:2011-10-20
Information query