Invention Grant
US08236838B2 Compounds, compositions and methods comprising isoxazole derivatives
有权
包含异恶唑衍生物的化合物，组合物和方法
- Patent Title: Compounds, compositions and methods comprising isoxazole derivatives
- Patent Title (中): 包含异恶唑衍生物的化合物，组合物和方法
-
Application No.: US12426876Application Date: 2009-04-20
-
Publication No.: US08236838B2Publication Date: 2012-08-07
- Inventor: Graham Peter Jones , Kevin James Doyle
- Applicant: Graham Peter Jones , Kevin James Doyle
- Applicant Address: US CA South San Francisco
- Assignee: Institute for OneWorld Health
- Current Assignee: Institute for OneWorld Health
- Current Assignee Address: US CA South San Francisco
- Agency: Foley & Lardner LLP
- Agent Antoinette F. Konski; Photon Rao
- Main IPC: A61K31/422
- IPC: A61K31/422 ; C07D261/08
Abstract:
The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-2 or encompassed by formulas I-II) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.
Public/Granted literature
- US20090264486A1 Compounds, Compositions and Methods Comprising Isoxazole Derivatives Public/Granted day:2009-10-22
Information query
IPC分类:
