Invention Grant
US08236809B2 Substituted 1,2,3-triazolopyrimidines for the inhibition of NAD(P)H oxidases and platelet activation
失效
用于抑制NAD（P）H氧化酶和血小板活化的取代的1,2,3-三唑并嘧啶
- Patent Title: Substituted 1,2,3-triazolopyrimidines for the inhibition of NAD(P)H oxidases and platelet activation
- Patent Title (中): 用于抑制NAD（P）H氧化酶和血小板活化的取代的1,2,3-三唑并嘧啶
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Application No.: US11579999Application Date: 2005-05-13
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Publication No.: US08236809B2Publication Date: 2012-08-07
- Inventor: Frank Tegtmeier , Ulrich Walter , Reinhard Schinzel , Kirstin Wingler , Peter Scheurer , Harald Schmidt
- Applicant: Frank Tegtmeier , Ulrich Walter , Reinhard Schinzel , Kirstin Wingler , Peter Scheurer , Harald Schmidt
- Applicant Address: DE
- Assignee: Vasopharm GmbH
- Current Assignee: Vasopharm GmbH
- Current Assignee Address: DE
- Agency: Acuity Law Group, PC
- Agent Michael A. Whittaker
- Priority: EP04011831 20040518
- International Application: PCT/EP2005/005272 WO 20050513
- International Announcement: WO2005/111041 WO 20051124
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P25/28 ; A61P19/02 ; A61P9/00 ; A61P35/00 ; A61P13/12
Abstract:
The invention relates to compounds of formula het-X-AB containing a N-heteroaryl moiety “het”, which is linked via X=sulfur to the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl moiety AB of the formula (II). The invention also relates to a process for the preparation of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidase-related diseases and disorders and inhibition of platelet activation.
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