Invention Grant
- Patent Title: Methods of modulating angiogenesis and screening compounds for activity in modulating angiogenesis
- Patent Title (中): 调节血管生成和筛选化合物调节血管生成活性的方法
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Application No.: US11521787Application Date: 2006-09-15
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Publication No.: US08236772B2Publication Date: 2012-08-07
- Inventor: John P. Cooke , Martin Ng , Jenny C. Wu , Edwin Chang
- Applicant: John P. Cooke , Martin Ng , Jenny C. Wu , Edwin Chang
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP.
- Agent Paula A. Borden
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K48/00 ; C07H21/04 ; A01N63/00

Abstract:
The present invention provides methods of modulating angiogenesis in an individual, as well as methods of identifying a candidate agent that modulates angiogenesis, where such methods involve modulating and identifying agents that modulate expression of gene products of a subset of genes concordantly-regulated by agonists of nicotinic acetylcholine receptor (nAChR), bFGF receptor, and VEGF receptor.
Public/Granted literature
- US20070135369A1 Methods of modulating angiogenesis and screening compounds for activity in modulating angiogenesis Public/Granted day:2007-06-14
Information query
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