Invention Grant
US08236562B2 Method for producing ready to use, antigen-loaded or unloaded, cryoconserved mature dendritic cells
有权
生产即用型，抗原载体或未加载的低密度成熟树突状细胞的方法
- Patent Title: Method for producing ready to use, antigen-loaded or unloaded, cryoconserved mature dendritic cells
- Patent Title (中): 生产即用型，抗原载体或未加载的低密度成熟树突状细胞的方法
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Application No.: US10362715Application Date: 2001-08-24
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Publication No.: US08236562B2Publication Date: 2012-08-07
- Inventor: Gerold Schuler , Beatrice Schuler-Thurner
- Applicant: Gerold Schuler , Beatrice Schuler-Thurner
- Applicant Address: US NC Durham
- Assignee: Argos Therapeutics, Inc.
- Current Assignee: Argos Therapeutics, Inc.
- Current Assignee Address: US NC Durham
- Agent Elaine Sale; Leigh Thorne
- Priority: DE10041515 20000824
- International Application: PCT/EP01/09790 WO 20010824
- International Announcement: WO02/16560 WO 20020228
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/00 ; C12N5/02
Abstract:
The invention relates to a method for producing ready to use, antigen loaded or unloaded, cryoconserved mature dendritic cells especially for the production of a vaccine containing said dendritic cells, wherein immature dendritic cells are cultivated in the presence of suitable maturation stimuli and the mature dendritic cells thus obtained are frozen. The dendritic cells can be loaded with antigen before freezing. The invention also relates to a vaccine which can be obtained according to the inventive method and to a composition containing frozen, mature dendritic cells which are loaded with antigen.
Public/Granted literature
- US20040253574A1 Method for producing ready to use, antigen loaded or unloaded, cryconserved mature dendritic cells Public/Granted day:2004-12-16
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