Invention Grant
- Patent Title: Efficient production of IgA in recombinant mammalian cells
- Patent Title (中): 在重组哺乳动物细胞中有效地产生IgA
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Application No.: US10644256Application Date: 2003-08-20
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Publication No.: US08236561B2Publication Date: 2012-08-07
- Inventor: David H. A. Jones , Abraham Bout
- Applicant: David H. A. Jones , Abraham Bout
- Applicant Address: NL Leiden
- Assignee: Crucell Holland B.V.
- Current Assignee: Crucell Holland B.V.
- Current Assignee Address: NL Leiden
- Agency: TraskBritt
- Priority: EP02077953 20020718
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N15/85
Abstract:
The invention provides an immortalized human retina cell expressing E1A and E1B proteins of an adenovirus, wherein the cell has recombinant nucleic acid encoding an IgA molecule in expressible format. Also provided is a method for recombinant production of an IgA molecule, the method involving culturing a cell of the invention and expressing the recombinant nucleic acid encoding an IgA.
Public/Granted literature
- US20050106722A1 Efficient production of IgA in recombinant mammalian cells Public/Granted day:2005-05-19
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