Invention Grant
- Patent Title: Promoter variants of the alpha-7 nicotinic acetylcholine receptor
- Patent Title (中): α-7烟碱乙酰胆碱受体的启动子变体
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Application No.: US12474402Application Date: 2009-05-29
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Publication No.: US08236500B2Publication Date: 2012-08-07
- Inventor: Sherry Leonard , Robert Freedman
- Applicant: Sherry Leonard , Robert Freedman
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Department of Veterans Affairs
- Current Assignee: The United States of America, as represented by the Department of Veterans Affairs
- Current Assignee Address: US DC Washington
- Agency: Medlen & Carroll, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention is directed to methods and compositions related to α7 acetylcholine nicotinic receptor genes, in particular, the human α7 nicotinic acetylcholine receptor gene. The human α7 nicotinic acetylcholine receptor gene is associated with the pathophysiological aspects of the disease schizophrenia. The present invention further provides methods and compositions to screen populations for abnormal α7 alleles, as well as methods and compositions for development of therapeutics.
Public/Granted literature
- US20100047795A1 Promoter Variants Of The Alpha-7 Nicotinic Acetylcholine Receptor Public/Granted day:2010-02-25
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