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US08236496B2 Use of gene activity classifiers for the in vitro classification of gene expression profiles of patients with infectious/non-infectious multiple organ failure 失效
使用基因活性分类器进行传染性/非感染性多器官功能衰竭患者基因表达谱的体外分类

  • Patent Title: Use of gene activity classifiers for the in vitro classification of gene expression profiles of patients with infectious/non-infectious multiple organ failure
  • Patent Title (中): 使用基因活性分类器进行传染性/非感染性多器官功能衰竭患者基因表达谱的体外分类
  • Application No.: US11909372
    Application Date: 2006-03-16
  • Publication No.: US08236496B2
    Publication Date: 2012-08-07
  • Inventor: Stefan Russwurm , Konrad Reinhart
  • Applicant: Stefan Russwurm , Konrad Reinhart
  • Applicant Address: DE Jena
  • Assignee: SIRS-Lab GmbH
  • Current Assignee: SIRS-Lab GmbH
  • Current Assignee Address: DE Jena
  • Agency: Patent Central LLC
  • Agent Stephan A. Pendorf
  • Priority: DE102005013013 20050321
  • International Application: PCT/EP2006/060780 WO 20060316
  • International Announcement: WO2006/100203 WO 20060928
  • Main IPC: C12Q1/68
  • IPC: C12Q1/68 ;  C12P19/34
Use of gene activity classifiers for the in vitro classification of gene expression profiles of patients with infectious/non-infectious multiple organ failure
Abstract:
The present invention relates to the use of gene activity markers for classification of patients suffering from infectious and non-infectious multiple organ failure, respectively.The present invention in particular relates to gene activity markers for classification of patients as “not infected without multiple organ failure” or as “not suffering from infectious multiple organ failure” or as “suffering from infectious multiple organ failure”, the gene activity markers being polynucleotides selected from the group consisting of: SEQ ID I.1, SEQ ID I.2, SEQ ID I.3, SEQ ID I.4, SEQ ID I.5, SEQ ID I.6, SEQ ID I.7, SEQ ID I.8 and SEQ ID I.9 or partial sequences thereof.
Abstract(Chinese):

本发明涉及基因活性标记物在分别感染和非感染性多器官功能衰竭患者分类中的应用。 本发明特别涉及将患者分类为“未感染无多器官功能衰竭”或“不患有感染性多器官功能衰竭”或“感染性多器官衰竭患者”的基因活性标志物，所述基因活性标记为 选自SEQ ID I.1，SEQ ID I.2，SEQ ID I.3，SEQ ID I.4，SEQ ID I.5，SEQ ID I.6，SEQ ID I.7， SEQ ID I.8和SEQ ID I.9或其部分序列。

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