Invention Grant
- Patent Title: Process and equipment for plasmid purification
- Patent Title (中): 用于质粒纯化的工艺和设备
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Application No.: US11327987Application Date: 2006-01-09
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Publication No.: US08236495B2Publication Date: 2012-08-07
- Inventor: Samuel Nochumson , Ross Durland , Audrey Yu-Speight , John Welp , Kuowei Wu , Rexford Hayes
- Applicant: Samuel Nochumson , Ross Durland , Audrey Yu-Speight , John Welp , Kuowei Wu , Rexford Hayes
- Agency: Ph. D., Borson Law Group, PC
- Agent D. Benjamin Berson
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C02F1/02 ; B01D15/00
Abstract:
A scalable alkaline lysis process, including procedures and devices for the isolation of large quantities (grams and kilograms) of plasmid DNA from recombinant E. coli cells. Effective, controllable, and economical operation, and consistent low level of host chromosomal DNA in the final plasmid product. Involves a series of new unit operations and devices for cell resuspension, cell lysis, and neutralization.
Public/Granted literature
- US20060106208A1 Process and equipment for plasmid purfication Public/Granted day:2006-05-18
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