Invention Grant
- Patent Title: Tumor specific oligosaccharide sequences and use thereof
- Patent Title (中): 肿瘤特异性寡糖序列及其用途
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Application No.: US10487203Application Date: 2002-08-20
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Publication No.: US08236487B2Publication Date: 2012-08-07
- Inventor: Jari Natunen , Susann Teneberg , Karl-Anders Karlsson , Tero Satomaa , Annamari Heiskanen
- Applicant: Jari Natunen , Susann Teneberg , Karl-Anders Karlsson , Tero Satomaa , Annamari Heiskanen
- Applicant Address: FI Helsinki
- Assignee: Glykos Finland Oy
- Current Assignee: Glykos Finland Oy
- Current Assignee Address: FI Helsinki
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: FI20011671 20010820
- International Application: PCT/FI02/00681 WO 20020820
- International Announcement: WO03/016915 WO 20030227
- Main IPC: C12Q1/00
- IPC: C12Q1/00
Abstract:
The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.
Public/Granted literature
- US20050014718A1 Tumor specific oligosaccharide sequences and use thereof Public/Granted day:2005-01-20
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