Invention Grant
US08236301B2 Lumican proteoglycan in the diagnosis and treatment of atherosclerosis
有权
Lumican蛋白多糖在动脉粥样硬化的诊断和治疗中的应用
- Patent Title: Lumican proteoglycan in the diagnosis and treatment of atherosclerosis
- Patent Title (中): Lumican蛋白多糖在动脉粥样硬化的诊断和治疗中的应用
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Application No.: US11918621Application Date: 2006-05-18
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Publication No.: US08236301B2Publication Date: 2012-08-07
- Inventor: James R. Stone
- Applicant: James R. Stone
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Edwards Wildman Palmer LLP
- Agent Peter C. Lauro, Esq.; Richard B. Emmons
- International Application: PCT/US2006/019505 WO 20060518
- International Announcement: WO2006/125171 WO 20061123
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K39/395
Abstract:
The invention relates to methods of reducing formation of atheromas and methods of treating atherosclerotic lesions and/or atherosclerosis by reducing the amount of lumican proteglycan in the intima or an artery or in the lesion. The invention also relates to methods of identifying subjects having or at risk of having atherosclerosis comprising detecting an increased amount of lumican proteoglycan in a subject.
Public/Granted literature
- US20090123457A1 Lumican proteoglycan in the diagnosis and treatment of atherosclerosis Public/Granted day:2009-05-14
Information query
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