Invention Grant
- Patent Title: Bisaminoethanethiol-targeting ligand conjugates and compositions
- Patent Title (中): 双氨基乙硫醇靶向配体缀合物和组合物
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Application No.: US12563724Application Date: 2009-09-21
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Publication No.: US08236279B2Publication Date: 2012-08-07
- Inventor: David J. Yang , Chun W. Liu , Dong-Fang Yu , E. Edmund Kim
- Applicant: David J. Yang , Chun W. Liu , Dong-Fang Yu , E. Edmund Kim
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Fulbright & Jaworski L.L.P.
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14
Abstract:
The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
Public/Granted literature
- US20100055035A1 BISAMINOETHANETHIOL-TARGETING LIGAND CONJUGATES AND COMPOSITIONS Public/Granted day:2010-03-04
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