Systems and methods for efficient instruction support of an multiple features for opcodes of an instruction set. A processor detects a fetched instruction of a computer program comprises an opcode corresponding to a plurality of functions. Each function corresponds to a different type of operation. The processor determines the received instruction corresponds to a feature requested by the computer program, such as a cryptographic algorithm. A determination is made as to whether hardware support exists for the feature. If hardware support exists for the feature, the instruction is executed on-chip by the hardware. Otherwise, software performs the operation corresponding to the instruction.