Embodiments of an image processing system and methods for aligning features suitable for use in early skin-cancer detection systems are described herein. Corresponding skin features between a reference image and a later-captured image are precisely aligned. Curvatures are used to align body outlines of corresponding images using body-background masks. An initial-displacement flowfield map, generated from the aligned body outlines, may be applied to a filtered version of the later-captured image to generate a pre-warped image. The pre-warped image and a filtered version of the reference image are divided into a plurality of overlapping chips and a correlation is performed between corresponding chips. A transformation map may be generated based on the chip correlations. This chipping process may be iterated for successively smaller chip sizes to generate a final transform map which may be applied to the later-captured image to generate a registered image having its skin features aligned with the reference image.