A driving circuit of a flat panel display can transfer a signal input from a decoder to a corresponding channel while minimizing a size of a MOS transistor for a switch or an amplification driver. The driving circuit of the flat panel display includes a first data signal processing unit for converting a first display information that will be displayed on the flat panel display into a positive gamma value, a second data signal processing unit for converting a second display information that will be displayed on the flat panel display into a negative gamma value, an output driving unit for outputting the negative and positive gamma values to the flat panel display, and a switch unit for selectively transferring the positive and negative gamma values to the output driving unit.