Invention Grant
- Patent Title: Purification method of lactone compounds containing unsaturated alkyl group by extraction with silver ion solution
- Patent Title (中): 用银离子溶液提取含有不饱和烷基的内酯化合物的纯化方法
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Application No.: US13051948Application Date: 2011-03-18
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Publication No.: US08193345B2Publication Date: 2012-06-05
- Inventor: Jae Jong Kim , Si Kyu Lim , Mi Ok Lee , Sang Myoun Lim , Bo-mi Lee , Dong Hwan Kim , Keum Soon Lee , Jeoung Hyun Ryu
- Applicant: Jae Jong Kim , Si Kyu Lim , Mi Ok Lee , Sang Myoun Lim , Bo-mi Lee , Dong Hwan Kim , Keum Soon Lee , Jeoung Hyun Ryu
- Applicant Address: KR Daejeon
- Assignee: Genotech Corp.
- Current Assignee: Genotech Corp.
- Current Assignee Address: KR Daejeon
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: KR10-2008-0091523 20080918
- Main IPC: C07D498/16
- IPC: C07D498/16
Abstract:
The present invention relates to a method for separating and purifying a lactone compound with an unsaturated alkyl group from a lactone compound with a saturated alkyl group which is an analog thereof. More specifically, the present invention relates to a method for effectively separating a lactone compound with an unsaturated alkyl group such as FK506 at high purity by extraction with a silver ion (Ag+) solution without use of column chromatography.
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