Invention Grant
US08193330B2 Polynucleotides comprising Neurogenin3 promoter and bHLH encoding domains
失效
包含Neurogenin3启动子和bHLH编码区的多核苷酸
- Patent Title: Polynucleotides comprising Neurogenin3 promoter and bHLH encoding domains
- Patent Title (中): 包含Neurogenin3启动子和bHLH编码区的多核苷酸
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Application No.: US10642093Application Date: 2003-08-14
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Publication No.: US08193330B2Publication Date: 2012-06-05
- Inventor: Michael S. German
- Applicant: Michael S. German
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis, LLP
- Agent James S. Keddie
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C12N15/85
Abstract:
The present invention features polypeptides having activity of human neurogenin3 (hNgn3), and nucleic acid encoding such polypeptide. The invention also features use of islet transcription factors such as hNgn3 to facilitate production of pancreatic islet cells from progenitor cells, and to facilitate insulin delivery by production of islet cells so produced.
Public/Granted literature
- US20040106555A1 Neurogenin3 and production of pancreatic islet cells Public/Granted day:2004-06-03
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