Invention Grant
- Patent Title: Fused and spirocycle compounds and the use thereof
- Patent Title (中): 熔融和螺环化合物及其用途
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Application No.: US11991626Application Date: 2006-09-08
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Publication No.: US08193208B2Publication Date: 2012-06-05
- Inventor: Zhengming Chen , Laykea Tafesse , Jiangchao Yao , Khondaker Islam
- Applicant: Zhengming Chen , Laykea Tafesse , Jiangchao Yao , Khondaker Islam
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- International Application: PCT/EP2006/008788 WO 20060908
- International Announcement: WO2007/028638 WO 20070315
- Main IPC: A61K31/438
- IPC: A61K31/438 ; C07D491/107
Abstract:
The invention relates to fused and spirocycle compounds of Formula I: or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein R1, R2, Q1-Q3, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20090118319A1 Fused and Spirocycle Compounds and the Use Thereof Public/Granted day:2009-05-07
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