Invention Grant
- Patent Title: Method of inhibiting complement activation with human anti-factor C3 antibodies and use thereof
- Patent Title (中): 用人抗因子C3抗体抑制补体活化的方法及其应用
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Application No.: US11690334Application Date: 2007-03-23
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Publication No.: US08192742B2Publication Date: 2012-06-05
- Inventor: Rekha Bansal
- Applicant: Rekha Bansal
- Applicant Address: US OH Cleveland
- Assignee: NovelMed Therapeutics
- Current Assignee: NovelMed Therapeutics
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
A method of inhibiting complement activation mediated by C3b inhibitors in a subject includes administering a C3B inhibitor to the subject to inhibit at least one of C3b binding to factors B and properdin, inhibit C3 cleavage, inhibit the activation of neutrophils, monocytes, platelets, and endothelium; or inhibit the formation of C3a, C5a, and MAC.
Public/Granted literature
- US20080233113A1 METHOD OF INHIBITING COMPLEMENT ACTIVATION WITH HUMAN ANTI-FACTOR C3 ANTIBODIES AND USE THEREOF Public/Granted day:2008-09-25
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