Invention Grant
- Patent Title: Pim kinase inhibitors and methods of their use
- Patent Title (中): Pim激酶抑制剂及其使用方法
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Application No.: US12380458Application Date: 2009-02-26
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Publication No.: US08168794B2Publication Date: 2012-05-01
- Inventor: Matthew Burger , Jiong Lan , Mika Lindvall , Gisele Nishiguchi , Michelle Tetalman
- Applicant: Matthew Burger , Jiong Lan , Mika Lindvall , Gisele Nishiguchi , Michelle Tetalman
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Michael G. Smith
- Main IPC: A61K31/4545
- IPC: A61K31/4545 ; C07D213/75 ; C07D417/12 ; C07D413/14
Abstract:
The present invention relates to new compounds of Formulas I and II, their tautomers, stereoisomers and polymorphs, and pharmaceutically acceptable salts, esters, metabolites or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the inhibition of Pim kinase activity and/or the prophylaxis or treatment of cancer.
Public/Granted literature
- US20100216839A1 Pim kinase inhibitors and methods of their use Public/Granted day:2010-08-26
Information query
IPC分类:
