Invention Grant
US08168775B2 Compositions and methods for inhibiting expression of transthyretin
有权
抑制转甲状腺素蛋白表达的组合物和方法
- Patent Title: Compositions and methods for inhibiting expression of transthyretin
- Patent Title (中): 抑制转甲状腺素蛋白表达的组合物和方法
-
Application No.: US12582669Application Date: 2009-10-20
-
Publication No.: US08168775B2Publication Date: 2012-05-01
- Inventor: Dinah Wen-Yee Sah , Gregory Hinkle , Rene Alvarez , Stuart Milstein , Qingmin Chen
- Applicant: Dinah Wen-Yee Sah , Gregory Hinkle , Rene Alvarez , Stuart Milstein , Qingmin Chen
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; C12N15/63 ; C12N15/85 ; A61K48/00
Abstract:
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
Public/Granted literature
- US20100120893A1 Compositions and Methods for Inhibiting Expression of Transthyretin Public/Granted day:2010-05-13
Information query
