Invention Grant
US08168766B2 Process of making 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleosides and intermediates therefor
有权
制备2-脱氧-2,2-二氟-D-呋喃核糖核苷的方法及其中间体
- Patent Title: Process of making 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleosides and intermediates therefor
- Patent Title (中): 制备2-脱氧-2,2-二氟-D-呋喃核糖核苷的方法及其中间体
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Application No.: US12550548Application Date: 2009-08-31
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Publication No.: US08168766B2Publication Date: 2012-05-01
- Inventor: Julian Paul Henschke , Yung Fa Chen , George Charles Schloemer
- Applicant: Julian Paul Henschke , Yung Fa Chen , George Charles Schloemer
- Applicant Address: TW Tainan
- Assignee: ScnioPharm Taiwan Ltd.
- Current Assignee: ScnioPharm Taiwan Ltd.
- Current Assignee Address: TW Tainan
- Main IPC: C07H13/02
- IPC: C07H13/02 ; C07H13/04 ; C07H13/08 ; C07H5/04 ; C07H19/06 ; C07H19/073 ; C07H19/16 ; C07H19/173
Abstract:
A compound of formula (A) or salt thereof: wherein each of R1, R2, and R3 independently represents hydrogen, alkyl, aryl, acyl, sulfonyl, or silyl; P represents hydrogen or a hydroxy protective group. This compound may be used an intermediate for making a 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleosides, such as gemcitabine.
Public/Granted literature
- US20100056771A1 Process of Making 2-Deoxy-2,2-Difluoro-D-Ribofuranosyl Nucleosides and Intermediates Therefor Public/Granted day:2010-03-04
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