Invention Grant
US08168633B2 Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
有权
噻唑并嘧啶及其作为磷脂酰肌醇-3激酶抑制剂的用途
- Patent Title: Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
- Patent Title (中): 噻唑并嘧啶及其作为磷脂酰肌醇-3激酶抑制剂的用途
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Application No.: US12986317Application Date: 2011-01-07
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Publication No.: US08168633B2Publication Date: 2012-05-01
- Inventor: Timothy Colin Hancox , Neil Anthony Pegg , Mandy Christine Beswick , Toby Jonathan Blench , Elsa Amandine Dechaux , Jahusz Jozef Kulagowski , Alan John Nadin , Stephen Price
- Applicant: Timothy Colin Hancox , Neil Anthony Pegg , Mandy Christine Beswick , Toby Jonathan Blench , Elsa Amandine Dechaux , Jahusz Jozef Kulagowski , Alan John Nadin , Stephen Price
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Alex Andrus
- Priority: GB0711344.2 20070612; GB0715677.1 20070810
- Main IPC: A61K31/5377
- IPC: A61K31/5377
Abstract:
Thiazolopyrimidine compounds of formula I, where W represents a thiazole ring, selectively inhibit the p110 delta subtype of PI3 Kinase (PI3K), and are useful for treating diseases and disorders arising from abnormal cell growth, function or behavior associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
Public/Granted literature
- US20110098270A1 THIAZOLOPYRIMIDINES AND THEIR USE AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3 KINASE Public/Granted day:2011-04-28
Information query
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