Invention Grant
- Patent Title: RNAi inhibition of alpha-ENaC expression
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Application No.: US12771614Application Date: 2010-04-30
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Publication No.: US08168606B2Publication Date: 2012-05-01
- Inventor: Gino Van Heeke , Emma Hickman , Henry Luke Danahay , Pamela Tan , Anke Geick , Hans Peter Vornlocher
- Applicant: Gino Van Heeke , Emma Hickman , Henry Luke Danahay , Pamela Tan , Anke Geick , Hans Peter Vornlocher
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Frank Wu
- Priority: EP07110376 20070615; EP07114265 20070813
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N5/00 ; C12Q1/68
Abstract:
The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.
Public/Granted literature
- US20100210514A1 RNAi Inhibition of Alpha-ENaC Expression Public/Granted day:2010-08-19
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