Invention Grant
US08168603B2 G-quartet oligonucleotides that target hypoxia-inducible factor 1-α (HIF1α)
失效
靶向缺氧诱导因子1-α（HIF1α）的G-四重寡核苷酸
- Patent Title: G-quartet oligonucleotides that target hypoxia-inducible factor 1-α (HIF1α)
- Patent Title (中): 靶向缺氧诱导因子1-α（HIF1α）的G-四重寡核苷酸
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Application No.: US12117877Application Date: 2008-05-09
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Publication No.: US08168603B2Publication Date: 2012-05-01
- Inventor: Naijie Jing , Yongli Guan
- Applicant: Naijie Jing , Yongli Guan
- Applicant Address: US TX Houston
- Assignee: Baylor College of Medicine
- Current Assignee: Baylor College of Medicine
- Current Assignee Address: US TX Houston
- Agency: Fulbright & Jaworski L.L.P.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12Q1/68 ; C07H21/04 ; C12N5/00
Abstract:
The present invention concerns particular G-quartet oligonucleotides that are employed for the treatment and/or prevention of cancer. In specific cases, the G-quartet oligonucleotides inhibit HIF-1α.
Public/Granted literature
- US20090075928A1 G-QUARTET OLIGONUCLEOTIDES THAT TARGET HYPOXIA-INDUCIBLE FACTOR 1-a (HIF1a ) Public/Granted day:2009-03-19
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