Invention Grant
- Patent Title: Method for preparation of hepatocyte using ES cell
- Patent Title (中): 使用ES细胞制备肝细胞的方法
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Application No.: US12225411Application Date: 2006-03-24
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Publication No.: US08168430B2Publication Date: 2012-05-01
- Inventor: Toyohiko Ariga , Taiichiro Seki , Go Watanabe , Hiroto Nakashima , Yuichi Hasebe
- Applicant: Toyohiko Ariga , Taiichiro Seki , Go Watanabe , Hiroto Nakashima , Yuichi Hasebe
- Applicant Address: JP Tokyo
- Assignee: Nihon University
- Current Assignee: Nihon University
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/JP2006/306783 WO 20060324
- International Announcement: WO2007/110966 WO 20071004
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A01N63/00

Abstract:
This invention relates to an agent for promoting differentiation of an ES cell, preferably an agent for promoting differentiation of an ES cell into a hepatocyte or a prophylactic agent for teratoma, comprising uPA. Furthermore this invention relates to a method of promoting differentiation of an ES cell, preferably a method of promoting differentiation of an ES cell into a hepatocyte, comprising the step of contacting uPA with the ES cell, or a method of preparing a hepatocyte comprising the step of contacting uPA with an ES cell to differentiate the ES cell into a hepatocyte.
Public/Granted literature
- US20100055762A1 Method for Preparation of Hepatocyte Using Es Cell Public/Granted day:2010-03-04
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