Invention Grant
- Patent Title: Modified lecithin-cholesterol acyltransferase enzymes
- Patent Title (中): 改性卵磷脂 - 胆固醇酰基转移酶
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Application No.: US12179815Application Date: 2008-07-25
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Publication No.: US08168416B2Publication Date: 2012-05-01
- Inventor: Tom Boone , David Park Meininger , Margrit Schwarz , Bei Shan , Wenyan Shen , Mingyue Zhou
- Applicant: Tom Boone , David Park Meininger , Margrit Schwarz , Bei Shan , Wenyan Shen , Mingyue Zhou
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Marshall, Gerstein & Borun LLP
- Agent Olga Mekhovich; Scott Ausenhus
- Main IPC: C12N9/10
- IPC: C12N9/10 ; A61K38/45 ; A61P9/00 ; C12P21/02
Abstract:
The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, coronary heart disease, thrombosis, and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.
Public/Granted literature
- US20090081182A1 Modified Lecithin-Cholesterol Acyltransferase Enzymes Public/Granted day:2009-03-26
Information query
