Invention Grant
US08168412B2 Method for producing optically-active amine compound, recombinant vector, and transformant containing the vector
有权
生产光学活性胺化合物，重组载体和含有该载体的转化体的方法
- Patent Title: Method for producing optically-active amine compound, recombinant vector, and transformant containing the vector
- Patent Title (中): 生产光学活性胺化合物，重组载体和含有该载体的转化体的方法
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Application No.: US12302460Application Date: 2007-05-28
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Publication No.: US08168412B2Publication Date: 2012-05-01
- Inventor: Shigeru Kawano , Noriyuki Ito , Yoshihiko Yasohara
- Applicant: Shigeru Kawano , Noriyuki Ito , Yoshihiko Yasohara
- Applicant Address: JP Osaka
- Assignee: Kaneka Corporation
- Current Assignee: Kaneka Corporation
- Current Assignee Address: JP Osaka
- Agency: Birch, Stewart, Kolasch and Birch, LLP
- Priority: JP2006-148623 20060529
- International Application: PCT/JP2007/060806 WO 20070528
- International Announcement: WO2007/139055 WO 20071206
- Main IPC: C12P13/00
- IPC: C12P13/00
Abstract:
The present invention relates to a method for producing an optically-active amine compound. The method is characterized by using a transaminase (A), an α-keto acid reductase (B), and an enzyme (C), each having specific properties, in an identical reaction system to convert a ketone compound into a corresponding optically-active amine compound in which a carbon atom with an amino group bonded thereto serves as an asymmetric point. The present invention also relates to a recombinant vector for use in the method. The present invention makes it possible to efficiently produce an optically-active amine compound.
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