Invention Grant
- Patent Title: Antibiotic clarithromycin micropellet compositions
- Patent Title (中): 抗生素克拉霉素微丸组合物
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Application No.: US10768562Application Date: 2004-01-30
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Publication No.: US08168228B2Publication Date: 2012-05-01
- Inventor: Indranil Nandi , Mintong Guo , Chad Michael Gassert , Franz Xaver Schwarz , Irina Kosilek
- Applicant: Indranil Nandi , Mintong Guo , Chad Michael Gassert , Franz Xaver Schwarz , Irina Kosilek
- Applicant Address: CH Basel
- Assignee: Sandoz AG
- Current Assignee: Sandoz AG
- Current Assignee Address: CH Basel
- Agency: Luedeka Neely Group, P.C.
- Main IPC: A61K9/50
- IPC: A61K9/50

Abstract:
An oral suspension comprising (a) an antibiotic composition which comprises coated micropellets and optionally one or more excipients, (b) additional excipients, and (c) a solvent, wherein said coated micropellets comprise (i) a core comprising at least one antibiotic; (ii) an inner coating comprising at least one cellulose polymer which is not an enteric coating polymer; and (iii) an outer coating comprising at least one enteric coating polymer, wherein said coated micropellets have a mean particle size of about 100 μm to about 650 μm. The oral suspension of the invention is characterized by a lack of bitter taste.
Public/Granted literature
- US20050084541A1 Antibiotic compositions Public/Granted day:2005-04-21
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