Invention Grant
US08168187B2 Nucleic acid and corresponding protein entitled 184P1E2 useful in treatment and detection of cancer
失效
核酸和相应的题为184P1E2的蛋白质可用于治疗和检测癌症
- Patent Title: Nucleic acid and corresponding protein entitled 184P1E2 useful in treatment and detection of cancer
- Patent Title (中): 核酸和相应的题为184P1E2的蛋白质可用于治疗和检测癌症
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Application No.: US12985245Application Date: 2011-01-05
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Publication No.: US08168187B2Publication Date: 2012-05-01
- Inventor: Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
- Applicant: Pia M. Challita-Eid , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
- Applicant Address: US CA Santa Monica
- Assignee: Agensys, Inc.
- Current Assignee: Agensys, Inc.
- Current Assignee Address: US CA Santa Monica
- Agency: Morrison & Foerster LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/30 ; C12N5/00
Abstract:
A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 184P1E2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 184P1E2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 184P1E2 can be used in active or passive immunization.
Public/Granted literature
- US20110110952A1 NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 184P1E2 USEFUL IN TREATMENT AND DETECTION OF CANCER Public/Granted day:2011-05-12
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