Invention Grant
- Patent Title: Compounds for tumor diagnosis and therapy
- Patent Title (中): 用于肿瘤诊断和治疗的化合物
-
Application No.: US12418563Application Date: 2009-04-03
-
Publication No.: US08168159B2Publication Date: 2012-05-01
- Inventor: Amin I. Kassis , Ravi S. Harapanhalli
- Applicant: Amin I. Kassis , Ravi S. Harapanhalli
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Edwards Wildman Palmer LLP
- Agent George W. Neuner; Mark D. Russett
- Main IPC: A61K51/00
- IPC: A61K51/00
Abstract:
The present invention discloses a method for the enzyme-mediated, site-specific, in-vivo precipitation of a water soluble molecule in an animal. The enzyme is either unique to tumor cells, or is produced within a specific site (e.g., tumor) at concentrations that are higher than that in normal tissues. Alternatively, the enzyme is conjugated to a targeting moiety such as an antibody or a receptor-binding molecule.
Public/Granted literature
- US20090285755A1 METHODS FOR TUMOR DIAGNOSIS AND THERAPY Public/Granted day:2009-11-19
Information query
