Disclosed is a device and method for generating a microbubble infused solution, the device having a cartridge including a first and second compartment separated by a small channel, wherein the cartridge is formed from a pliable and gas-impermeable material, and having a bubble solution inside the cartridge. Applying pressure to a substantial portion of an outer side of a selected compartment forces at least a portion of the bubble solution inside the selected compartment through the small channel to an unselected compartment and form microbubbles inside the cartridge.