Described techniques increase runtime performance of workloads executing on a hypervisor by executing virtualization-aware code in an otherwise non virtualization-aware guest operating system. In one implementation, the virtualization-aware code allows workloads direct access to physical hardware devices, while allowing the system memory allocated to the workloads to be overcommitted. In one implementation, a DMA filter driver is inserted into an I/O driver stack to ensure that the target guest physical memory of a DMA transfer is resident before the transfer begins. The DMA filter driver may utilize a cache to track which pages of memory are resident. The cache may also indicate which pages of memory are in use by one or more transfers, enabling the hypervisor to avoid appropriating pages of memory during a transfer.