A driving system and method for liquid crystal display is disclosed. The system stores only the driving values corresponding to specific grayscale values of pixels on a current frame and specific grayscale values of pixels on a previous frame. The stored driving values are then used by an operation processing unit of the system to calculate out driving values to be applied to the current frame. Moreover, the system is provided with a logic judging unit for preventing the noises of the frame from being overdriven.