Invention Grant
- Patent Title: Methods and means for removal of a selected DNA sequence
- Patent Title (中): 用于去除所选DNA序列的方法和方法
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Application No.: US11910515Application Date: 2006-03-31
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Publication No.: US08148607B2Publication Date: 2012-04-03
- Inventor: Kathleen D'Halluin , Rene Ruiter
- Applicant: Kathleen D'Halluin , Rene Ruiter
- Applicant Address: BE Diegem
- Assignee: Bayer CropScience N.V.
- Current Assignee: Bayer CropScience N.V.
- Current Assignee Address: BE Diegem
- Agency: Hunton & Williams LLP
- Priority: EP05075781 20050404
- International Application: PCT/EP2006/003086 WO 20060331
- International Announcement: WO2006/105946 WO 20061012
- Main IPC: C12N15/82
- IPC: C12N15/82
Abstract:
A method is described for the exact removal of a selected subfragment from a DNA molecule by intrachromosomal recombination between two directly repeated DNA sequences using a rare-cleaving double stranded break inducing DNA endonuclease expressed under control of a micro-spore specific promoter. This method can be applied in a method for the exact exchange of a target DNA fragment for a DNA fragment of interest in plant cells and plants.
Public/Granted literature
- US20090089890A1 METHODS AND MEANS FOR REMOVAL OF A SELECTED DNA SEQUENCE Public/Granted day:2009-04-02
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