Invention Grant
US08148577B2 Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
有权
可用作抗寄生虫和抗癌治疗剂的多胺和赖氨酸特异性脱甲基酶抑制剂
- Patent Title: Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
- Patent Title (中): 可用作抗寄生虫和抗癌治疗剂的多胺和赖氨酸特异性脱甲基酶抑制剂
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Application No.: US12763722Application Date: 2010-04-20
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Publication No.: US08148577B2Publication Date: 2012-04-03
- Inventor: Patrick M. Woster , Tracey Boncher , Robert A. Casero
- Applicant: Patrick M. Woster , Tracey Boncher , Robert A. Casero
- Applicant Address: US MD Baltimore US MI Detroit
- Assignee: The Johns Hopkins University,Wayne State University
- Current Assignee: The Johns Hopkins University,Wayne State University
- Current Assignee Address: US MD Baltimore US MI Detroit
- Agency: Edwards Wildman Palmer LLP
- Agent Peter F. Corless; Melissa Hunter-Ensor, Esq.
- Main IPC: C07C279/12
- IPC: C07C279/12 ; C07C279/18 ; A61K31/155
Abstract:
Polyamine, polyamine/guanidino, and polyamine/biguanide compounds are disclosed. The compounds are useful as anti-cancer and anti-parasitic treatments. The compounds are also useful as inhibitors of the enzyme lysine-specific demethylase-1.
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