Invention Grant
US08148497B2 Binding molecules capable of neutralizing rabies virus and uses thereof
有权
能够中和狂犬病病毒的结合分子及其用途
- Patent Title: Binding molecules capable of neutralizing rabies virus and uses thereof
- Patent Title (中): 能够中和狂犬病病毒的结合分子及其用途
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Application No.: US12459661Application Date: 2009-07-06
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Publication No.: US08148497B2Publication Date: 2012-04-03
- Inventor: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan de Kruif
- Applicant: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan de Kruif
- Applicant Address: NL Leiden
- Assignee: Crucell Holland B.V.
- Current Assignee: Crucell Holland B.V.
- Current Assignee Address: NL Leiden
- Agency: TraskBritt
- Priority: WOPCT/EP2004/050943 20040527; WOPCT/EP2004/051661 20040729; WOPCT/EP2004/052286 20040923; WOPCT/EP2004/052772 20041103; WOPCT/EP2005/050310 20050125; WOPCT/EP2005/050953 20050303
- Main IPC: C07K16/10
- IPC: C07K16/10 ; C12N15/13 ; C12P21/08 ; C12Q1/70 ; A61K39/42

Abstract:
The invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the post-exposure prophylaxis of rabies.
Public/Granted literature
- US20100272724A1 Binding molecules capable of neutralizing rabies virus and uses thereof Public/Granted day:2010-10-28
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