Invention Grant
- Patent Title: Multivalent antibody constructs
- Patent Title (中): 多价抗体构建体
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Application No.: US12367219Application Date: 2009-02-06
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Publication No.: US08148496B2Publication Date: 2012-04-03
- Inventor: Melvyn Little , Sergej Kipriyanov
- Applicant: Melvyn Little , Sergej Kipriyanov
- Applicant Address: DE Heidelberg
- Assignee: Deutsches Krebsforschungszentrum
- Current Assignee: Deutsches Krebsforschungszentrum
- Current Assignee Address: DE Heidelberg
- Agency: Perkins Coie LLP
- Agent Patrick D. Morris
- Priority: DE19819846 19980505
- Main IPC: C12P21/08
- IPC: C12P21/08 ; A61K39/00 ; C12P21/06
Abstract:
The present invention relates to a multivalent Fv antibody construct having at least four variable domains which are linked with each over via the peptide linkers 1, 2 and 3. The invention also concerns expression plasmids which code for such an Fv antibody construct and a method of producing the Fv antibody constructs as well as their use.
Public/Granted literature
- US20100099853A1 Multivalent Antibody Constructs Public/Granted day:2010-04-22
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